Firefighters used an outside ladder to get to a man trapped on the second floor because the stairs had burned away.
Of the 15 students on the bus, ranging in age from 15 to 17-years-old, three were transported to be checked out as were three children in one of the other vehicles.
An off duty St. Louis firefighter sprung into action when he spotted a pickup truck in the River des Peres.
Captain Dan Sutter said two people took shelter in the basement and, remarkably, were not hurt.
When firefighters got to the three-story brick building at the corner of Magnolia and Louisiana, flames had engulfed the basement then quickly filled the first floor.
St. Louis Fire Department Capt. Dan Sutter said firefighters found Salsman and one of her two dogs together in the house.
Fire Department spokesman Dan Sutter says flames were already shooting through the roof of the three-story residential building when they arrived.
St. Louis Fire Captain Dan Sutter says crews were called to a home in the 5300 block of Greer around 2 a.m.
Firefighters were able to pull the unidentified woman from the rubble of the three-story building that collapsed Thursday afternoon.
Cause of fire is under investigation