St. Louis police are searching for gray Chrysler 200 in connection with the crime.
The Madison County state’s attorney’s office says two men are charged with murder.
Cedric Anderson was sentenced for the November, 2010 killing of David Foote in front of Anderson’s preteen daughter and Foote’s wife.
Prosecutors allege Carl Kelley shot three people in October. One, 38-year-old Byron Gallion, died.
Police chief identifies Adrian Perry as the 21st murder victim of the year.
Police aren’t sure if the incidents are related.
Sheriff Gary Toelke says family members found 57-year-old William Osborne Sr. shot to death in his home on Osborne Lane last evening.
Police say 29-year-old Ryan Faulstich was shot multiple times.
One person shot dead inside home on North 40th Street
St. Louis police say the 39-year-old victim was shot several times.