Adrian Houston of University City is charged with two counts of first-degree murder and other charges in the deaths of 32-year-old Tony Jordan and 25-year-old Jessica Thompson.
Errick Owens, 20, is in custody in connection with the death of Juliette Cleveland-Davis.
Torrence Neal, 25, of St. Louis and Antrell Teen, 21, of Bridgeton are charged with murder in the case.
Police say they may be able to release names on Monday.
Prosecutors in St. Clair County have charged 22-year-old Treveon Burrage of East St. Louis with first-degree murder.
Police say a man shot and killed 2 people in an Arkansas residence, 1 person in a business before being found dead of a gunshot wound in a vehicle.
Police identify victim as 29-year-old Ibsa Alemu
Cameras around North St. Louis may be able to solve 19-year-old, Jose Johnson’s shooting death that happened Thursday afternoon.
Police say victim Wendy Hall-Onkle knew her attacker.
City police say two killed, one critically-injured in 4000 block of Peck.