Reward Offered for Unique Gun Possibly Used in Murder SpreeThe Erma Werke ET-22 may have been used in six murders in four states, including one in St. Charles.
Missouri Man Killed While Walking Along I-65 in IndianaTroopers found his car parked along the highway about a mile away.
Teens Ask Indiana City to Ban Saggy PantsWearing pants low enough to expose underwear could soon be against the law in Gary, Indiana.
Ohio Second in Fatal Workplace Accidents in OSHA RegionData from the U.S. Occupational Safety and Health Administration show Ohio with the second-highest number of workers killed on the job in the agency's Midwest region this past fiscal year, behind Illinois.
Ghosts: U.S. Senior Amateur Golf Returns to St. LouisNext year the U.S. Senior Amateur comes to St. Louis and Old Warson Country Club. But this isn’t about a look ahead. It’s about a look to the past.
Two Indiana Teens Rescued from Garden of the GodsTwo Indiana teenagers have been rescued after becoming lost in southern Illinois' Garden of the Gods wilderness area.
Man on Trial in HIV Exposure Case Previously Tested Positive A 23-year-old man accused of exposing other gay men to HIV while attending college in suburban St. Louis tested positive for the virus that causes AIDS two years earlier in Indiana.
TIAM SundayThe Delta Queen, Jane Dueker and Harry Hamm on "Furious"
Guide To March Madness' Final FourA quick start travel guide to help prepare you for your trip to the Final Four in Indianapolis.
Treacherous Travel Conditions In Snowy Southern IndianaTwo counties declared states of emergency Monday to keep motorists off slick roads after a winter storm dumped several inches of snow across parts of southern Indiana.
19 Injured On St. Louis to New York Greyhound BusPhillip Lloyd, the driver of the stolen 1999 Ford Mustang, died at the scene of the Sunday morning collision on Interstate 70 near Richmond.
Midwest Storms Cause More Than $100 Million In DamageIt's been a brutal storm season for the Midwest as powerful winds, tornadoes, and storms pound homes and businesses.